MolecularEpidemiology of orf513-Bearing Class 1 Integrons in MultiresistantClinical Isolates from ArgentineanHospitals

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Molecular epidemiology of orf513-bearing class 1 integrons in multiresistant clinical isolates from Argentinean hospitals.

The spread of orf513-bearing class 1 integrons is associated with bla(CTX-M-2) in gram-negative clinical isolates in Argentina, with In35 being the most frequently found integron (74%). Among 65 isolates without bla(CTX-M-2), only one harbored a novel orf513-bearing class 1 integron with the dfrA3b gene. The finding of orf513 not associated with class 1 integrons in two gram-positive strains in...

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Common regions e.g. orf513 and antibiotic resistance: IS91-like elements evolving complex class 1 integrons.

The ability of bacteria to procure, sometimes rearrange, and evince acquired DNA continues to impress us-even more so if this genetic plasticity involves the sequestering of antibiotic resistance genes. The acquisition of genes in bacteria is often facilitated by transposons, integrons and archetype insertion elements. Recently however, a new element, 'orf513', has been increasingly associated ...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 2003

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.47.12.3945-3949.2003